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Inflammatory Bowel Disease Inflammatory Bowel Disease Treatment

When Medication is Not Enough: Surgery for Inflammatory Bowel Disease


Medically Reviewed On: April 25, 2003

Erica Heilman

It is estimated that as many as one million people in the United States live with inflammatory bowel disease, or IBD. IBD actually refers to a group of bowel conditions, characterized by inflammation of the gastrointestinal tract. Most often the affected areas are in the small intestine or colon, and the most common forms of IBD are Crohn's disease and ulcerative colitis. The symptoms of IBD can be painful and sometimes disabling, and many people with IBD must rely on medications for a lifetime. For some, however, medications cause intolerable side effects; for others, medication simply does not work. IBD can cause such difficult and compromising complications that no medical therapy is sufficient treatment.

When medication fails, or the pain and inconvenience of IBD is unbearable, surgery becomes an important option. Dr. Mark Reiner is an assistant clinical professor of surgery at the Mount Sinai Hospital in New York City. Below, he discusses surgical options for Crohn's disease and ulcerative colitis.

When is surgery an option in people with inflammatory bowel disease?
In order to understand when an IBD patient needs surgery, we have to understand why they need it, and there are really two times when patients need surgery for inflammatory bowel disease, the most common of those diseases being ulcerative colitis or Crohn's.

One is when there is a failure of medical management. They either cannot tolerate the medication because they've had an adverse side effect or the medication has not been successful in treating their disease. They have profound symptoms from the disease that affects their quality of life. This is an occasion for surgery.

The second reason a patient may need surgery is that they develop a complication specific to their disease. Complications are unique to the different conditions that fall under inflammatory bowel disease, and these various complications may require emergency surgery. Crohn's disease and ulcerative colitis are each associated with different complications.

What are some of the reasons that people with Crohn's disease in particular might need surgery?
Approximately 50-75% of patients with Crohn's disease may require surgery sometime in their lives. It can be the result of quality of life issues or failure of medication or one of a variety of different complications. Crohn's patients are also at greater risk of cancer of the small bowel.

Complications of Crohn's include toxic megacolon, which is a massive dilatation of the colon that may lead to perforation, bleeding, intestinal or bowel obstruction, abscess formation or fistulization—which are abnormal openings from one loop of bowel to another part of the bowel, to the skin or to another organ of the body.

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